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Vitamin B12 Deficiency and Management During Pregnancy In addition to anaemia, symptoms of vitamin B12 deficiency may include: Fatigue Breathlessness Nervous system symptoms such as numbness, tingling or poor balance Poor concentration or memory Paleness Mood changes, including low mood, anxiety or disrupted sleep Some women are more susceptible to vitamin B12 deficiency than others

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For Lebers optic atrophy or smokers blindness, the usual dose starts at 1000mcg, given daily for 2 weeks, followed by twice weekly