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Collectively, maternal obesity appears to overstimulate placental nutrient-sensing networks (mTOR, insulin/IGF-1, PPAR) while inhibiting energy homeostasis pathways (AMPK, SIRT1), leading to excessive nutrient transfer and long-term metabolic consequences for the offspring [49,53,55,56,57,58]

References 1.Lokeshwar SD, Patel P, Fantus RJ, Halpern J, Chang C, Kargi AY, et al

Hormonal changes due to rapid weight loss may lead to some women having menstrual irregularities

Natural food sources are almost entirely animal-derived: meat, fish, eggs and dairy, plus fortified foods such as some plant milks and yeast extracts