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demonstrated that substituting hydrophobic amino acids with less lipophilic residues can reduce hemolytic activity without compromising antimicrobial activity (Vincenzi et al., 2024a)

Methylation of B3GAT2 (beta-1,3-glucuronyltransferase 2), CCNA1 , TFPI2 , TWIST1 , VIM , and ZNF793 (Zinc finger protein 793) can be confirmed using MethyLight PCR and Cytosponge, a non-endoscopic tool ( TFPI2 has shown promise as a diagnostic biomarker for BE

cremoris NZ9000 [66] indicating the clear role of this enzyme in oxidative stress protection mechanism in LAB

With the advancement of global industrialization, its incidence continues to rise, particularly in newly industrialized regions, which not only severely impairs patients' quality of life but also emerges as a major public health concern threatening digestive system health, accompanied by a substantial healthcare burden, thus necessitating the development of more effective and safer individualized treatment strategies