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& Valle, D.) (McGraw-Hill, New York, USA, 2005)

Epidemiological studies of cataract prevalence indicate that riboflavin intakes of 1.6 to 2.2 mg/day may reduce the risk of developing age-related cataracts

The microbial translocation through the disrupted tight junctions of GI cells promotes systemic inflammation and can alter the BBB or cause other direct CNS effects via the Vagus nerve