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Rapid changes in neural activity have been previously reported from rat hippocampal-entorhinal complex slice cultures exposed to nanogram concentrations of TNF-, which was in part attributed to reduced glutamate transport activity in astrocytes (Zou and Crews, 2005)

In 3-KO mice, these reductions were absent, reinforcing the idea that 3-AR plays a necessary role in regulating the response of brown adipose tissue to these agents [2]

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Others experience feeling unusually cold , likely related to reduced caloric intake and metabolic changes