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Liu Z, Xiao M, Mo Y, Wang H, Han Y, Zhao X

Likewise, in an in vitro study, niacin (VB3) significantly reduced the secretion of the pro-inflammatory cytokine IL-8 from human hepatocytes (HepG2 and primary cells) that were stimulated with palmitic acid

(approximately 0.1%) ( 2 to generate significant amounts of O 2 -, the precursors to most ROS (Sohal, 1993)

Peroxiredoxin (PRX) was discovered in 1988 and is a novel peroxidase capable of reducing both hydroperoxides and peroxynitrate with the use of electrons provided by a physiological thiol like TRX (204, 205, 327)