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Similar results were found for dorsal muscle lipid content that showed a decreasing trend with dietary betaine supplementation, albeit not significantly different to HFD ( Figure 2 )

Duration: At least 36 months of regular use is recommended for sustained results, though early improvements may be seen in 812 weeks

Drug therapy, including corticosteroids, calcineurin inhibitors, hydroxychloroquine, hyaluronic acid, and mTOR inhibitors, as well as non pharmacological treatments such as autologous platelet concentrates and photodynamic therapy, are the pillars of clinical management

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