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Walter Nolen 3-1-4

Data availability The authors declare that all the relevant data supporting the findings of the study are available in the article and its Supplementary Information files, or from the corresponding author upon request

SIRT3 is indispensable in the pathological process of DKD affected by the (Pro)renin receptor (PRR)

Among these oncometabolites, 2HG has gained prominence due to its chiral forms, D -2HG and L -2HG, which structurally mimic -KG and competitively inhibit -KG-dependent dioxygenases