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Further, the patient was heterozygous for the AMN variant c.1006 + 34_1007-31 del mutation with duplication of exons 23, indicating a definite diagnosis of typical IGS

The metabolic gene signature might also explain the differential efficacy of gemcitabine over pemetrexed in SCC compared to AdC when paired with cisplatin 58 and the preferred choice of combined gemcitabine and a platinum-based drug for first-line treatment of SCC patients

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Then, Tukey HSD post-hoc test was used when the assumption of equality of population variances of the groups was provided, otherwise the Games-Howell post-hoc test was used