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While vitamin B12 deficiency can lead to the underdevelopment of the brain in early life, it can also lead to severe symptoms in adulthood, ranging from dementia, memory loss and cognitive/intellectual decline

Possibly a specialized lymphoid tissue, such as that of the thymus which is most active in embryonic and early independent life and decays soon after, is engaged in this function' (Jerne, Nov 1955)

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The production of SAMe plummets, meaning the body can no longer efficiently synthesize the myelin needed to protect peripheral nerves, leading to tingling, numbness, and neuropathic pain