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This consequently results in Nrf2 stabilization, accumulation and translocation into the nucleus where it combines with the corresponding antioxidant-response elements (ARE) switching on the transcription machinery of antioxidant target genes such as heme oxygenase-1 (HO-1), and glutathione reductase (GR) enzymes [22]

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Given that endophytes are often a strong source of antibacterial compounds 68