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Am J Respir Crit Care Med (1994) 149(3 Pt 1):81824

Dimethyl Fumarate (DMF, Tecifidera ) is an NRF2 activator in clinical use for the treatment of relapsing forms of MS and psoriasis

The aim of the study was to evaluate the effect the dual action on GPBAR1 and RORt, by the administration of Allo-LCA, in preventing the development of NASH inflammation and fibrosis

Chen found in human melanoma cells that silencing iPLA2 would enhance the sensitivity to p53-mediated ferroptosis without significant effects on cells that usually express iPLA2, suggesting that iPLA2 can inhibit p53-mediated ferroptosis, and p53-driven ferroptosis is independent of GPX4 [41]