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828 The GPX4-binding protein OTU deubiquitinase 5 (OTUD5) reduces the sensitivity of cells to ferroptosis by stabilizing GPX4

10.1073/pnas.1603244113 Proc

Article Discussion on paper presented by Rice TW, T2N0M0 esophageal cancer

This work develops the first mathematical model for the GSH antioxidant system in the outer retina, capturing the most essential components for formation of ROS, GSH production, its oxidation in detoxifying ROS, and subsequent reduction by NADPH