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In this Application Note, as an example, we report with some detail on the deamidation of one common IgG1 tryptic peptide for a stress test consisting of exposure at alkaline conditions: GFYPSDIAVEWESNGQPENNYK

This comprehensive immune response should be exploited in next-generation vaccines to complement antibodies in the global population, which is currently overwhelmingly seropositive against SARS-CoV-2 spike following vaccination and/or infection

And for researchers navigating this landscape, SeekPeptides provides the most comprehensive, up-to-date resource for understanding these options, with evidence-based guides, detailed protocol databases, and a community of experienced researchers who track every development in real time

Philip Pape: 6:54 Confounding variables are the wild cards