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Rather than sitting on an intact stratum corneum (as it would in topical-only application), PRP reaches the fibroblasts and endothelial cells that need to respond to it

High triglycerides (a type of body fat), blood sugar spikes, and increased risk of pancreatic disease Liver problems, shown by elevated liver enzymes in blood tests or, rarely, jaundice Digestive issues, including nausea or diarrhea, especially in those with inflammatory bowel disease Blood disorders, including low platelet or red blood cell counts Allergic reactions, often due to capsule preservatives Respiratory or vocal symptoms, especially in people with asthma Menstrual irregularities, including missed periods Accutane can remain in sperm for weeks after stopping intake

Keep a photo log to track changes that may be too gradual to notice day to day