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In the current study, with the help of pharmacological methods and animal models, we demonstrate that astrocytic DRD2 induces GSH synthesis via PKM2-mediated Nrf2 transactivation

A very large proportion of human breast adenocarcinomas (~75%) expressed CB2R and expression was strongly associated with HER2+ tumors, while no association was found between CB2R expression and HR+ or TNBC