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Science 246 , 382385 (1989)

Dehydration and electrolyte imbalance: Dehydration and depletion of essential minerals such as potassium, magnesium, and calcium can trigger muscle spasms, especially during or after intense physical activity in hot weather

Taking vitamin B12 can lead to relief from any of these symptoms

Exercise has been shown to upregulate GLUT4 production, offering insight into how physical activity contributes to energy balance and glucose regulation