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Indeed, astaxanthin is known for its ability to stabilize cell membranes and neutralize free radicals through its polyene chain, while capsaicin could potentially modulate the electronic state of astaxanthin's polyene chain

Li J-h, Chen Y, Ye Z-h, Chen L-p, Xu J-x, Han J et al (2024) Suppression of MyD88 disturbs gut microbiota and activates the NLR pathway and hence fails to ameliorate DSS-induced colitis

Abbreviations CALCOCO2: Calcium binding and coiled-coil domain-containing protein 2 DPP: Diabetes Prevention Program ECM: Extracellular matrix ER: Endoplasmic reticulum GLP-1: Glucagon-like peptide-1 GWAS: Genome-wide association studies HNF1A: Hepatocyte nuclear factor 1- IGT: Impaired glucose tolerance ITFG3: Integrin FG-GAP repeat containing 3 PE: Pancreatic elastase SIDD: Severe insulin-deficient diabetes TMAO: Trimethylamine N -oxide UPR: Unfolded protein response References Esser N, Utzschneider KM, Kahn SE (2020) Early beta cell dysfunction vs insulin hypersecretion as the primary event in the pathogenesis of dysglycaemia

H., Hong, K