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Aging cell 2018;17, e12780, doi:10.1111/acel.12780

Subcutaneous, in the abdomen

Although our in vitro studies in lymphoid leukaemia cell lines suggest that the combination of polyphenols and topoisomerase II inhibitors may selectively enhance antitumour effects in tumour versus normal HSCs, future in vivo studies are needed to confirm that these effects are maintained in vivo

From the bile, they come into the intestine where enzyme glucuronidase is present which hydrolyses the conjugate and the active drug is reabsorbed from the small intestine into the systemic circulation and the process is called enterohepatic circulation [11]