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These are illustrative, not a contraindication checklist there is no contraindication table because there is no approved indication: Known or suspected malignancy the proposed pro-angiogenic mechanism (particularly via VEGFR2-Akt-eNOS signaling) raises theoretical concerns about tumor vascularization that have not been characterized in humans Pregnancy or breastfeeding no human reproductive or developmental toxicology data exists Known peptide hypersensitivity or a history of serious peptide-related adverse reactions Athletes subject to anti-doping testing BPC-157 is prohibited by WADA under S0 in-competition and out-of-competition

Induction of multidrug resistance associated protein 2 in tamoxifen-resistant breast cancer cells

For further reading, see Bioregulator Peptides for Aging, The Hallmarks of Aging: Which Peptides Target Which?, and Best Anti-Aging Peptides in 2026

Partial hydration during warm transit degrades the peptide without visible signs