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Nikolaus Friedreich and degenerative atrophy of the dorsal columns of the spinal cord

16 It has been shown that influenza viruses induce oxidative stress mediated by an excess of ROS and a decrease of reduced glutathione, and that such conditions favour viral replication, with glutathione depletion pivotal for the folding and maturation of the viral glycoprotein and therefore viral replication

Since glutathione, which is ultimately a metabolic intermediary, is transported by so many of the MRP transporters, I backtracked its metabolic pathway MRP Isoforms There are 12 known human isoforms as summarised - MRP1 Long MRP Role excretes a broad range of endogenous and exogenous substances

as a hydrophilic molecule, GSH is added to other lipophilic toxins or wastes prior to entering biliary excretion