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The inactivation of GPX4 can be achieved through both indirect approaches, including GSH depletion, as well as direct methods involving pharmacological or genetic interventions

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[DOI] [Google Scholar] 49.Marginean C.M., Pirscoveanu D., Popescu M., Vasile C.M., Docea A.O., Mitru R., Mrginean I.C., Iacob G.A., Firu D.M., Mitru P

However, the precise mechanisms by which SCFAs influence brain physiology and behavior remain to be fully clarified, underscoring a promising avenue for developing novel CNS therapies