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Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted dihexa human clinical trials studies DHX PNB 0408 Dihexa Peptide: Benefits, Mechanism, and Dihexa UK: Evidence Based Peptide Research Guide Growth factors and their peptide mimetics for treatment of traumatic brain injury ScienceDirect
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