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Ha, C., Ullman, T

The study of levels from redox-active elements in cerebrospinal fluid of amyotrophic lateral sclerosis patients carrying disease-related gene mutations shows potential copper dyshomeostasis

The main phenotype of loss-of-function mutations in arGSTs is the decreased content of anthocyanins ( 1 ) 19,20,21,22,23,24,25,26,27,28 and proanthocyanidins 27 , which can be well explained by an incomplete biosynthesis due to the absence of an essential enzyme

Similarly, a recent meta-analysis of 15 cohort studies with over 86,000 PD cases and nearly 30 million subjects, found that prediabetic patients have a 4% increased risk of PD compared to individuals with normal blood glucose level [20]