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Description

High-dose biotin, also known as vitamin B7, can affect assays that use a biotin and streptavidin binding step, and the direction of the error depends on the assay format, with competitive designs prone to falsely high results and sandwich designs to falsely low ones

Referenced Citations Kraus D

[73] As noted above, the completely synthetic laboratory synthesis of B 12 was achieved by Robert Burns Woodward and Albert Eschenmoser in 1972, though this process has no commercial potential, requiring more than 70 steps and having a yield well below 0.01%

Description Overview Cyanocobalamin is a synthetic form of vitamin B12 used to treat B12 deficiency, improve cognitive function, and boost mood and energy levels