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Table 4 Age-standardized mortality and YLDs rates of cardiovascular disease subtypes attributable to smoking in 1990 and 2021, and time trends from 1990 to 2021 (based on GBD 2021 study data) DISCUSSION This study provides a comprehensive descriptive analysis of the burden of CVD attributable to smoking at the global, regional, and national levels from 1990 to 2021

Importantly, this does not necessarily equal a 95 percent reduction in risk, and IQOS ILUMA is not risk-free

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