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[DOI] [PubMed] [Google Scholar] Rivard A, Fabre JE, Silver M, Chen D, Murohara T, Kearney M, Magner M, Asahara T, Isner JM

Methods: 8wks old, male AJ and C57Bl/6J mice were fed ad libitum either a low-fat control diet (LFD: 13% saturated fat) or a Western-style high-fat, high-fructose diet (HFD: 42% saturated fat) for 12 weeks then fasted for 4h prior to sacrifice

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Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery