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The method according to claim 15, wherein the one or more compounds have the structure of formula (1a): R 1 is selected from the group consisting of H, alkyl, aryl, C 1-6 alkyl-aryl, C 1- 6 alkyl-phenolyl, and C 3-10 carbocycle, wherein each of the alkyl, aryl, C 1-6 alkyl- aryl, C 1-6 alkyl-phenolyl, and C 3-10 carbocycle are optionally substituted with one or more atoms or groups

The article was refined and used for scientometric analysis

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An agonistic monoclonal anti-body (mAb) of TREM2, AL002, was shown to induce microglia proliferation and reduces pathology in AD mice (Wang S