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Calfee et al

These technological strides have facilitated the development of protocols for in-utero treatment of various fetal conditions, such as congenital diaphragmatic hernia, myelomeningocele, pulmonary sequestration, fetal hydrothorax, and urinary tract obstructions [141]

5 Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia

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