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Ethanolamine and phosphoethanolamine inhibit mitochondrial function in vitro : implications for mitochondrial dysfunction hypothesis in depression and bipolar disorder

The accumulation of misfolded proteins leads to severe ER stress (ERS), which activates the unfolded protein response (UPR) (Oakes and Papa, 2015)

Human pGST2-TSG101 UEV plasmid was obtained from Addgene (Addgene #184810) and cDNA for M95A, N45A, M95A/N45A (Twist Biosciences) was subcloned into the same plasmid

These variations cause inconsistencies in bioactive compound composition and concentration, hindering quality control and reproducibility in research and clinical practice