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IL-6-STAT3 signaling as a potential cause of the ARDS via cytokine storms in COVID-19 patients IL-6 amplifier, machinery for excessive inflammation SARS-CoV-2 infection induces the endocytosis of ACE2 together with SARS-CoV in target cells including epithelial cells and endothelial cells, resulting in an increase of serum angiotensin II (Ang II) levels due to the reduction of ACE2 surface expression (Fig

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Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy

Tuckey RC, Cheng CYS, Slominski AT