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Oral B12 is most effective for people who: Follow a diet that includes plants Experience mild symptoms Need daily support to stay healthy Like taking supplements at home Do not have absorption problems The American Academy of Family Physicians explains that taking B12 works well to treat mild issues and for general supplementation, provided there are no absorption problems

Side effects are rare but can include mild irritation at the injection site

Interestingly, several in vitro studies of experimentally induced G6PD-d in human monocytes and endothelial cells have demonstrated that exposure to hyperglycemia or free fatty acids alone, as seen in diabetes or hyperlipidemia, decrease G6PD activity