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Metabolomics analysis of the 3D L-02 cell cultures revealing the key role of metabolism of amino acids in ameliorating hepatotoxicity of perfluorooctanoic acid

Key points Microplastics and nanoplastics (MNPs) are increasingly detected in human cardiovascular tissues, including blood, atherosclerotic plaques and myocardium, suggesting systemic distribution and potential involvement in cardiovascular disease pathogenesis