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Moreover, TEC kinases are involved in TCR activation cascades in T cells identified in patients with AA, making their inhibition a relevant therapeutic target in this disease.8 Recently, the MoA of ritlecitinib and baricitinib has been reviewed in the context of AA pathophysiology

To further investigate these metabolic differences, the major metabolic enzymes involved in OXPHOS or glycolysis were analyzed by immunoblotting

It prevails mostly in the elderly, rendering many factors as possible causative agents, which potentially contribute to the disease pathogenicity cumulatively