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While both fungal acne and closed comedones can appear similar, several key differences help in distinguishing between the two: Feature Fungal Acne Closed Comedones Appearance Itchy, red bumps White or flesh-colored bumps Itchiness Yes No Common Locations Chest, back, forehead Face (especially forehead, chin, cheeks) Causes Overgrowth of Malassezia yeast Clogged hair follicles due to oil and dead skin Treatment Antifungal medications Exfoliation, retinoids, salicylic acid Fungal acne, medically known as Pityrosporum folliculitis, is often exacerbated by warm, humid environments, making it more prevalent in tropical climates or during the summer months

Haddad HW, Malone GW, Comardelle NJ, Degueure AE, Kaye AM, Kaye AD (2022) Aducanumab, a novel anti-amyloid monoclonal antibody, for the treatment of Alzheimers disease: a comprehensive review

and other myeloid cells, CD11bLy6GF4/80

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