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A recent study examined the association between on-treatment weight loss and risk of DILI from tuberculosis treatment and reported that weight loss of 2 kg or more within 4 weeks, concomitant hepatitis C, older age and multi-drug resistant TB were independently associated risk factors [40]

Human TRX has been initially identified as a factor responsible for induction of the A subunit of interleukin-2 receptor which is now known to be under the control of NFKB

Reversing the Warburg effect by using drugs to intervene in the metabolic behavior of tumor cells so that their main energy production pathway changes from glycolysis to OXPHOS, may be a promising therapeutic strategy for treating such tumors

Cell 178:12051221 ( e1217 ) Chun LJ, Tong MJ, Busuttil RW, Hiatt JR (2009) Acetaminophen hepatotoxicity and acute liver failure