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Increasing Fpn levels were linked to reduced Mn accumulation in both the cerebellum and cortex of mice treated with Mn (Yin et al., 2010), further confirming that Fpn removes Mn and reduces Mn-induced neurotoxicity

Inhibition of TrxR by auranofin can lead to elevated ROS and RNS levels, apoptosis, and decreased cell proliferation

If the compound binds to the receptor, the binding of labeled ligand to the receptor is inhibited as determined by a reduction of labeled ligand which binds to the receptors

The role of adaptive immune responses in the context of nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma (HCC) has been investigated (Ma et al