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At first the bodies of vegetarians and vegans did not produce much TMAO even when they took supplements, but after a few weeks they did, Hazen's team reported in the Journal of Clinical Investigation." In Medical Express on December 10, 2018 it was reported, "The findings suggest that measuring and targeting TMAO levels - something doctors can do with a simple blood test - may be a promising new strategy for individualizing diets and helping to prevent heart disease

Pharmacokinetic modeling of ascorbate diffusion through normal and tumor tissue

That can be done through sweating out toxins through FIR saunas, removing them with glutathione, which makes toxins water soluble so they can be properly eliminated, or by supporting other detox pathways like methylation some individuals dont methylate properly