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Ultimately, while pharmacological interventions can offer symptomatic relief for ME/CFS patients, an understanding of the potential benefits and risks associated with such treatments is crucial

(2) molecular dynamics simulated annealing restraining FOXO4 FH (without flexible regions) harmonically to its template structure (using a non-crystallographic force constant of 10,000 kcal mol 1 2 ), with additional dihedral angle restraints from 1 H, 15 N, and 13 C chemical shifts using TALOS-N 56 , hydrogen bond restraints (region p53 residues 48-55

504 Moreover, mitoQ aids in slowing aging by alleviating oxidative stress and inflammation, improving metabolism, and protecting mitochondrial function