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The 6 mg kg 1 DOX/LAAM GSH-CQD group showed the most efficient tumor growth inhibition with a 1.39-fold increase in relative tumor volume within 14 days, whereas the tumors in the DOX, Doxil, saline, and LAAM GSH-CQD groups increased by 3.34, 3.32, 3.68 and 4.24 times, respectively (Fig