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When combining the plasma EBV DNA load and methylation test pattern in plasma samples, the sensitivity was 0.97 and the specificity was 0.99 for population screening of NPC

Chinen I, Shimabukuro M, Yamakawa K, Higa N, Matsuzaki T, Noguchi K, Ueda S, Sakanashi M, Takasu N (2007) Vascular lipotoxicity: endothelial dysfunction via fatty-acid-induced reactive oxygen species overproduction in obese Zucker diabetic fatty rats

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Furthermore, the lobular distribution is dependent on dose with higher doses tending to produce centrilobular plus mid-lobular (Figure 4) and even panlobular hepatocellular hypertrophy