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These results are consistent with animal models of CRS in which tumor-infiltrating macrophages have been identified as a major source of IL-6 (32, 33)

In the IMPACT-TWIN system, the target POI sequence is cloned between two mini-inteins, where the vector is designed to produce a POI with a specific intein fused to either its N or C-terminus

Emideltide Free Peptide The sequence is commonly written as H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH