glutathione and napqi Metabolic pathway for formation detoxification by conjugation Biopharmaceutics and Drug Disposition |
Biopharmaceutics and Drug Disposition Pharmacology Journal Wiley Online Library Unveiling the molecular basis of paracetamol induced hepatotoxicity: Interaction of N acetyl p benzoquinone imine with mitochondrial succinate dehydrogenase ScienceDirect A) The CID pathways of N acetyl p benzoquinone imine glutathione Download Scientific Diagram Alcohol and paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting
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