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RCT: NAC Augmentation of Clozapine Neill et al 11 described an investigator-initiated, industry-independent, moderately large (n = 84), well-designed, well-conducted, well-analyzed, 52-week RCT of NAC (2 g/d) in schizophrenia patients with persistent symptoms that were refractory to at least 3 classes of antipsychotic drugs as well as to 6 months of treatment with their current medication, clozapine

If you smoke and consume alcohol then avoid them at least 2 weeks before treatment

Cold insulin can cause discomfort and local irritation upon injection, which can be minimized by allowing the insulin vial to reach room temperature

For targeted drug delivery, particle size control is crucial for the aerosols to bypass mucosal defences, and to be absorbed through the alveoli once the target area is reached