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Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia

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This is complemented by the incretin effect, insulin-sensitising properties, and promotion of subcutaneous fat accumulation mediated by GIP, as well as the thermogenic and lipolytic actions of GCG (Table 2).54 Its structure resists degradation by DPP-4 and enables binding to albumin, resulting in a half-life of six days, which allows for once-weekly subcutaneous administration

Research is ongoing, and we do not promise specific outcomes