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(2009) Effectiveness of vitamin B12 in treating recurrent aphthous stomatitis: a randomized, double-blind, placebo-controlled trial

B12 is naturally found in animal foods

Stomach issues, such as gastritis, infection with Helicobacter pylori or bariatric surgery (reducing stomach size) can all significantly reduce B12 absorption (Sobczyska-Malefora et al., 2021)

As stated in the proposed rule, even where one provision refers to a second provision, the preamble and the regulatory text clarify the intent of the agency that the two provisions will be severable if one provision were to be invalidated in whole or in part