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Description

The only large study of healthy adults examining B12 supplement safety found no association between B12 supplementation and increased mortality at any dose, including 1,000 g/day or more

Their beneficial effect does not involve the whole gastrointestinal tract, and they are regularly applied in wound healing studies with different carriers [7]

Patients should be instructed to rotate injection sites to minimize the risk of injection site reactions and to avoid injecting into areas that are tender, bruised, red, or hard