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Current GSH treatment for neurodegenerative disorders has been focused largely on trying to bypass the BBB (Liu et al., 2017)

Ferrostatin-1 significantly mitigated these effects suggesting that lipid peroxidation drives this state

Many of the processes that drive the glycolytic switch in M1 macrophages are downregulated in M2 macrophages (Figure 4)

[7] [8] [9] Additionally, metabotropic glutamate receptors may modulate synaptic plasticity by regulating postsynaptic protein synthesis through second messenger systems