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Antioxidant-rich compounds reduce ROS production, protecting neurons from oxidative stress-induced apoptosis (Simunkova et al., 2019)

77 Wang et al 78 found that CYP2E1-targeting RNAi delivered via lipid nanoparticles alleviated hepatic lipid accumulation, inflammation, and fibrosis in ALD mice, suggesting its therapeutic potential for ALD

Polyphenols and Oxidative Stress Polyphenols are renowned for their potent antioxidant properties, which play a critical role in mitigating oxidative stress, a key contributor to the pathogenesis of numerous chronic diseases, including neurodegenerative disorders, cardiovascular diseases, and cancer (Saeed et al

Similarly, it has been reported that Madin-Darby canine kidney cells infected with Sendai virus rapidly lost GSH, without increase in the oxidized products