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In contrast, both CJC-1295 and tesamorelin function upstream by engaging the GHRH receptor, leading to increased growth hormone release and subsequent activation of the IGF-1 pathway

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Sermorelin mimics natural growth hormone-releasing hormone, stimulating the pituitary through the GHRH receptor pathway to support pulsatile GH release

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Berger M, Nelson B, Markulev C, et al

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Protein Expr Purif 3(2):108113 Fekkes P, Driessen AJ (1999) Protein targeting to the bacterial cytoplasmic membrane

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